Interferon-𝝰 in the causal pathway of Sjögren Disease

Sjögren's Disease (SjD) is a chronic, systemic immunological disorder with poorly defined initiating and driving immune pathways. While there is evidence linking the potent antiviral cytokine Interferon-alpha (IFN-α) to SjD, it has been unclear whether IFN-α directly drives the disease. A recent study presented at the European League Against Rheumatism …