Drug Development Executive

Drug Development Executive

Basic/Translational Sciences

Can PD-1 Agonists Halt Sudden Death in Athletes with Hypertrophic Cardiomyopathy?

Eswar Krishnan, MD's avatar
Eswar Krishnan, MD
Jul 14, 2025
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In February 2025, the sudden death of 22-year-old Portuguese soccer player Diogo Jota during a match stunned the sports world. Autopsy findings pointed to hypertrophic cardiomyopathy (HCM), a genetic condition characterized by abnormal thickening of the heart muscle, impairing its ability to pump blood effectively. HCM is a leading cause of sudden cardi…

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